The San Francisco 49ers (frequently referred to as the Niners) are a professional American football team. The team plays their home games in San Francisco, California, while the club's headquarters and practice facility are located in Santa Clara, California. They currently belong to the Western Division of the National Football Conference (NFC) in the National Football League (NFL).

The 49ers began play in 1946 as a charter member of the All-America Football Conference and joined the NFL in 1950 after the AAFC merged into the older league. The team currently shares the record for most Super Bowl victories (5) with the Dallas Cowboys and the Pittsburgh Steelers.